Radiochemistry Services
At Pre-therapeutic, we provide expert radiochemistry support tailored to early-stage development of diagnostic and therapeutic radiopharmaceuticals. From labelling strategy to automation and formulation, our services are designed to accelerate your radiochemical workflows and ensure robust, translatable methods for clinical development.
Our Capabilities
We work across a broad range of radionuclides, providing customised support for both small molecules and biological constructs. Our experience spans:
Radionuclide labelling with:
- Positron emitters (e.g. ¹⁸F, ⁶⁴Cu, ⁶⁸Ga)
- Gamma emitters (e.g. ⁹⁹ᵐTc, ¹³¹I)
- Beta and alpha emitters (e.g. ¹⁷⁷Lu, ²²⁵Ac)
Radiolabelling assays for:
- Small molecules
- Peptides
- Antibodies and antibody fragments
Formulation Development
Formulation development to support stability and delivery.
Lipophilicity And Stability Assessments
Lipophilicity and stability assessments to guide early design decisions.
Optimisation And Automation
Optimisation and automation of labelling protocols, including cassette-based and module-based systems.
Scalability planning
Scalability planning for preclinical and early clinical use.
Why Work With Us?
Radiochemistry requires precision, flexibility, and a deep understanding of both chemistry and regulatory expectations. At Pre-therapeutic, we bring all of this together to help you:
- Select the right radionuclide and labelling strategy
- Develop efficient, reproducible radiolabelling protocols
- Ensure your formulation is stable, compliant, and ready for in vivo or clinical use
- Transition smoothly from manual methods to automated synthesis
Whether you are working with a new tracer or developing a radiotherapeutic, we offer the hands-on expertise needed to support you from concept to clinic.